Friday, August 27, 2010

Study links dogs not cats to kids asthma risk

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A Greenland sled dog puppy takes a close see at a caller in Tasiilaq Aug 3, 2009.

Credit: Reuters/Bob Strong

NEW YORK (Reuters Health) - For young kids at higher-than-average risk of asthma, carrying a dog around the residence competence enlarge the chances of building the lung disease, a new investigate suggests.

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The study, that followed 380 young kids at increasing risk of asthma due to family history, found that those unprotected to comparatively high levels of dog allergen at the age of 7 were some-more expected to have asthma.

In contrast, there was no attribute in in in between cat-allergen bearing and a child"s risk of asthma, according to commentary published in the biography Pediatric Allergy and Immunology.

Exactly since dogs were compared to a higher risk of asthma, whilst cats were not, is not wholly clear. But one cause competence be endotoxin, a piece constructed by germ that is well known to trigger inflammation in the airways, explained lead researcher Dr. Chris Carlsten, of Vancouver General Hospital in British Columbia, Canada.

Carlsten and his colleagues found that young kids unprotected to dog allergen at home were not at increasing risk of building an immune-system sensitization to dog allergen itself. Therefore, larger bearing to endotoxin competence at slightest partly insist the organisation in in in between carrying a dog in the home and a child"s risk of asthma.

"Dogs lend towards to have a lot of endotoxin on them, since they"re dogs," Carlsten told Reuters Health. In contrast, cats have most less, he said.

So should family groups with a story of asthma or allergies opt for a kitten over a puppy, or no feathery pets at all?

"This investigate doesn"t answer it," Carlsten said. "And in general, there is not sufficient justification to suggest for or opposite pets."

He pronounced that for now, his recommendation to kin is to bottom the preference on their family"s enterprise to have a pet, rather than the intensity goods on asthma risk.

The commentary are formed on 380 young kids who were at increasing asthma risk since at slightest one first-degree relations (meaning a parent, kin or child) had the lung disease or dual or some-more first-degree kin had alternative allergies, such as eczema or grain fever.

The children"s mothers were recruited for the investigate during pregnancy, and researchers totalled the levels of 3 allergens -- cat, dog and dust mite -- in the families" homes, intermittently over the child"s initial year of hold up and again when they were 7 years old.

At the outset, rounded off half of the family groups were incidentally reserved to an involvement directed at obscure the child"s risk of building allergies and asthma. That enclosed enlivening mothers to breastfeed for at slightest 4 months, and carrying kin extent their children"s bearing to dust mites, pets and tobacco smoke.

Carlsten"s group found that bearing to higher levels of dog allergen -- at slightest 2 micrograms per gram of residence dust -- at age 7 was compared with a scarcely three-fold enlarge in the risk of asthma compared with obtuse dog-allergen exposures. But that was usually in between young kids in the involvement group; seventeen of 97 young kids unprotected to higher levels of dog allergen at home had asthma at age 7.

Neither cat nor dust-mite bearing in decline or at age 7 was compared to the risk of asthma. Children with high dust-mite bearing were, however, some-more expected to show sensitization -- an defence complement greeting during skin contrast -- to dust-mite allergen.

According to Carlsten, the commentary underscore the complexity of the attribute in in in between indoor-allergen exposures and children"s asthma risk. More research, he said, is still indispensable to assimilate those intricacies.

Because the stream investigate enclosed usually young kids at towering risk of asthma, it is not transparent either the commentary competence additionally request to young kids at normal risk.

SOURCE: Pediatric Allergy and Immunology, online Mar 19, 2010.

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